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Databases | FELICS
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With funding from EMBL, the European Commission, The USA's National Institutes of Health, industry and various national research funders, the FELICS partners have built a range of core biomolecular databases, e.g. EMBL-Bank, Ensembl, GO, InterPro, Reactome, Medline. With FELICS funding, the EBI will provide transnational access to this broad range of databases, many of which are created by the FELICS partners (along with others being the products of collaborations with third parties outside FELICS, and having other sources of funding). Most of the FELICS resources will be dedicated to the development of a coherent subset of these databases.


Database/Activity Core objectives jras Lead partner
Genome Reviews To make fortnightly releases of Genome Reviews, updated with the latest data; to expand the scope to cover lower eukaryotic and viral genomes; and to enrich the content through direct manual curation of the Genome Reviews database jra01 EBI
Integr8 To develop indices to track genes, transcripts and proteins independently of their representation in individual resources; to enhance the Integr8 portal, primarily through increased support for comparative genomic and proteomic analysis; and to develop additional visualisation tools to support data search and display jra02 EBI
IntAct To implement international standards, to develop additional analysis tools, optimise performance, to build infrastructure for mandatory journal submissions and data exchange, and to improve data completeness and quality through expert curation jra03 EBI
ArrayExpress To simplify the submission process; scale up and unify the tools for managing submissions; improve user access to the data; improve quality control for the submitted data; support new standards; maintain a comprehensive archive; populate the gene-centric data warehouse; develop a gene expression atlas jra04, jra05 EBI
ChEBI To create a public database for biologically relevant "small molecules" by developing data submission tools, developing standard representations of chemical entities in other databases, generating 2D structures and providing rich search methods jra06 EBI
MSD To improve automation of the interaction between data submitters and the database, enhancing the archive of structural data and web based data deposition tool (AutoDep); to extend the query visualisation to include all the richness of the MSD; and to improve mechanisms for integration of data from unstructured text sources (e.g. MEDLINE) jra07, jra08, jra09 EBI
ENZYME and IntEnz To identify enzymes that perform new reactions; to link EC numbers to sequences; to retrieve cofactor information from literature and 3D structure databases. This will be used to create and improve enzyme entries in UniProt and to create new entries in IntEnz and ENZYME jra10 SIB
GPSDB To maintain a complete database of synonyms/homonyms for gene/protein names in order to enable interoperability between different information resources jra11 SIB
BRENDA To substantially diminish the data backlog in BRENDA, and to make available a public downloadable release twice per year, to integrate BRENDA with the other biological databases, and improve methods of querying it jra12, jra13 TUBS
PatentSeqDB To create a non-redundant collection of patent sequences to enable rapid comparison of new sequences with the information in the patent literature jra14 EPO
Patent Data Capture To develop standards and provide a complete workflow to collect and publish high quality sequence data from the EPO and national Patent offices; to streamline the verification and publication processes jra15 EPO